What's New

The Clinical and Scientific Basis of Myalgic Encephalomyelitis / Chronic Fatigue Syndrome reference book now available for free download. More information...

Arrange a video interview with Dr. Hyde over Skype. More information...

The Nightingale Research Foundation is a Canadian registered charitable organization dedicated to the study and treatment of Myalgic Encephalomyelitis (M.E.) and Chronic Fatigue Syndrome (CFS) and related illnesses.

We have been investigating M.E. and CFS patients since 1984. These thousands of case studies have formed the basis of our research into the causes and treatment for symptoms, and have led to a continual enhancement of our diagnostic protocols. We are now integrating the knowledge gained from this case-based research as we re-define the disease “of a thousand names”.

We collaborate with other medical organizations worldwide, and disseminate information to researchers, to the legal and advocate community, to healthcare professionals, and to patients and their caregivers.


We chose the Tiger, a natural killer, as our logo because one of the first scientific benchmarks of M.E. and CFS was the fact that patients lacked active natural killer cells, an essential part of the immune system.

We chose Nightingale as our name in honour of Florence Nightingale who fell ill with an infectious disease during her service in the Crimean War. Despite her severe disability, she went on to reform both public health and health care, helping to bring medicine and especially the care and treatment of the ill patient into the Twentieth Century.